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Thyroid Peroxidase(TPO) [PT0857]

Product code: EM60134

  • Overview

  • Product name Thyroid Peroxidase(TPO)
  • Molecular Wt 103 kDa
  • Description This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
  • Species reactivity Human
  • Tested applications WB
  • Antibody type Mouse Monoclonal Antibody
  • Immunogen Synthesized peptide derived from human Thyroid Peroxidase(TPO)
  • Positive control Glandular pool- thyroid, Spleen, Thyroid.
  • Conjugate Non-conjugated
  • Clone number PT0857
  • Alternative names MSA antibody
    PERT_HUMAN antibody
    TDH2A antibody
    Thyroid microsomal antigen antibody
    Thyroid peroxidase antibody
    Thyroperoxidase antibody
    TPO antibody
    TPX antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Purity Immunogen affinity purified.
  • Subcellular location Membrane.
  • Database links SwissProt: P07202 Human
  • Applications

    WB: 1:500-1:2000

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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